Integrative Computational Biology Lab

We are an integrative computational biology lab at UTMB in Galveston, TX — a coastal island about 50 miles southeast of cental Houston. We develop computational approaches that integrate structural modeling, molecular biophysics, multi-omic data, and ML/AI to understand how proteins interact, how these interactions change across biological contexts, and how they collectively shape cellular and disease processes. Our long-term goals are to (1) understand disease mechanisms through molecular interaction networks and (2) identify new therapeutic targets for protein engineering, drug discovery, and vaccine development.

Our lab is part of the Department of Biochemistry & Molecular Biology and the Sealy Center for Structural Biology and Molecular Biophysics within the School of Medicine. UTMB was established in 1891 as the first medical school in the University of Texas System. Today, it is home to the Galveston National Laboratory, a leading high-biosafety research facility in the United States, and is a institutional member of the Texas Medical Center (TMC), a world-renowned medical center.