We are an integrative computational biology lab at UTMB in Galveston, TX — a coastal island just southeast of Houston. We develop computational methods, incorporating chemistry-, physics-based, data- and Artificial Intelligence (AI)-driven approaches, and apply them to study Protein-Protein Interactions (PPIs) regarding their molecular biophysics and system-level interaction patterns. Our long-term goals are to 1) understand disease mechanisms by exploiting the predicted PPI networks, 2) narrow down key protein targets for mutation design, drug discovery and vaccine development.

Our lab is part of Department of Biochemistry & Molecular Biology and Sealy Center for Structural Biology and Molecular Biophysics in the UTMB School of Medicine. Founded in 1891, UTMB was the first medical school in Texas and the nation's first unified public medical school and hospital. It is home to The Galveston National Laboratory, one of the two National Biocontainment Laboratories (BSL-4) in the US. UTMB is one of the academic and research institutions within the Texas Medical Center (TMC), the world's largest, top-tier medical center.