We are an integrative computational biology lab at UTMB in Galveston, TX — a coastal island just southeast of Houston. We develop computational methods that incorporate chemistry-, physics-based, data- and artificial intelligence (AI)-driven approaches, and apply them to study protein-protein interactions (PPIs) focusing on their molecular biophysics and system-level interactions. Our long-term goals are to 1) understand disease mechanisms by exploiting the predicted PPI networks, 2) narrow down key protein targets for mutation design, drug discovery and vaccine development.

Our lab is part of the Department of Biochemistry & Molecular Biology and the Sealy Center for Structural Biology and Molecular Biophysics within the UTMB School of Medicine. UTMB is the oldest medical school in Texas and is home to the Galveston National Laboratory, a leading high-biosafety level (BSL-4) research facility in the United States. UTMB is also a member institution of the Texas Medical Center (TMC), the world's largest and a leading medical center.